The Witcher 3 – Mutations system explained

The Witcher 3: Blood and Wine introduces a bit more beyond its new area and new quests, with some completely new mechanics coming into play. Here you’ll learn all about the mutation system, which when used in conjunction with other skill upgrades can add a new dimension to your gameplay.

If you’re looking for more help, our Witcher 3 walkthrough can help.

The Witcher 3: The Blood and Wine Mutations

Once you’ve completed the Turn and Face the Strange side quest, you’ll gain access to a new upgrade system for Geralt. By spending upgrade points and using Greater Mutagens, you can add new bonuses to make Geralt stronger in combat, as well as unlock additional skill slots to use. Only one mutation can be active at a time and abilities placed in new slots must match the color of the active mutation, but combining the two can provide big upgrades; for example, Bloodbath along with four red Greater Mutagens, each maxed out with other red abilities. In theory, it can give you up to a 435% increase in attack power against some enemies.

Level 1 mutations cost 2 skill points and require 2 major mutagens of the appropriate color, level 2 mutations require 3 skill points and 3 major mutagens, and combo mutations require 5 skill points and 2 major mutagens of one color and 3 of the other.

Red mutations

  • Deadly Counter: Sword attacks deal 25% more damage to monsters or humans immune to counterattacks. For all other enemies, performing a counterattack when they are at 25% health or less will trigger an auto finisher.
  • Bloodbath: Each fatal blow of your sword triggers a finisher or dismemberment, and each hit you land will increase your attack power by 5% (up to a maximum of 250%) until the fight ends or you take damage. (Requires deadly counter)

Blue mutations

  • Magical Sensitivities: Signals can generate critical hits. Critical chance and damage increase with sign intensity.
  • Piercing Cold: Aard gains a 25% chance to freeze opponents, and if the explosion knocks them back as well, it will kill them instantly. Enemies that escape freezing take 1922 damage. (Requires magical sensitivities)

Green mutations

  • Toxic Blood: Each time you take damage, the attacker takes 1.5% of the damage they dealt for each point of your toxicity level.
  • Euphoria: Each point of Toxicity increases sword damage and Signal Intensity by 0.75%. (Requires toxic blood)

Red+blue mutations

  • Adrenaline Rush: When engaging in combat with more than one enemy, attack power and signal strength increase by 30% for each additional opponent for the first 30 seconds, after which they drop by 10%. (Requires Blood Bath and Biting Cold)
  • Conductor Magic: Drawn Magical, Unique, and Warlock Swords increase sign damage by 50%. (Requires Cold Piration)
  • Second Life: If your Vitality reaches 0, you regain 100% and gain brief invulnerability. The effect has a 3 minute cooldown. (Requires adrenaline)

Red+green mutations

  • Cat Eyes: Crossbow base damage is increased from 119 to 899, critical chance is increased by 50%, and bolts will pierce, stun, or knock down opponents. Enemies at full health will take 15% damage when shot. (Requires Bloodbath and Euphoria)
  • Mutated Skin: Each point of adrenaline decreases the damage you take by 15%. (Requires Euphoria)
  • Metamorphosis: Critical effects on enemies will trigger a random decoction (up to a maximum of 2) from your supply for 2 minutes at no toxicity cost, and as a bonus, also enhances Witcher Sense in dark areas. (Requires cat eyes)

Our Witcher 3 walkthrough and guide can help you through the main story, including the Wandering in the Dark and Family Matters quests and, eventually, one of several Witcher 3 endings. There’s also plenty of additional content, including Witcher 3 contracts, the White Orchard quests, the Velen quests, the Novigrad quests, and the Skellige Isles quests. Elsewhere, learn about the best Witcher 3 builds, the best Witcher 3 mods, how to make money in Witcher 3, find Places of Power locations, and learn how to do Witcher 3 crafting and alchemy. And when you’re done with it all . Those: We can help you through the expansions with our Hearts of Stone and Blood and Wine walkthrough.

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